That's amazing and.congratulations. Now.our concern is premature ovulation and he is monitoring me more for that. RE recommended MDL high dose protocol, 600 iu follistim, low Hcg. Afte, Hi all, MDL looks for those littlefollies who are hiding and then all of a sudden they start to grow. And can someone generally explain the 'steps' to me? I did do both natural start and primed and my response was the same. does your doctor use a medication called "orlissa" ? Def try the microdose lupron flare and let us know how it turns out!!!! Hi, I'm 40 did my first IVF in October with an antagonist protocol (AMH 4.86). And this time we are also going to do 225 follistim (x2/day) and 75 menupur (x2/day). Our most common protocol utilizes Lupron as a trigger instead of hCG to mature follicles prior to egg collection. Are you sure you want to block this member? The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. In Focus. V-dot patches(20)=estrogen :), I'm confused by all the information out there for women over 40. Life is wild just never give up. Learn more about, Twins & Multiples: Your Tentative Time Table. 9dp5dt Beta 1 = 344!! %PDF-1.4 % think twice before sharing personal details, foster a friendly and supportive environment, remove fake accounts, spam and misinformation, delete posts that violate our community guidelines, reviewed by our medical review board and team of experts. In addition, your chance of developing ovarian hyperstimulation syndrome is less with GnRH antagonist protocols. My AFC was 7 on day 3. Stage IV Endo. When you all say protocol what do you mean? My doctor refunded some costs and wants me to try again. Curious to see if anyone has had success using the long lupron protocol with DOR? The use of Lupron to trigger egg maturation over the past 4-5 years has gained popularity when given in a single higher dose (4mg) with aggressive supplementation of estrogen and progesterone following the egg retrieval. We had 3 failed IUIs- great response, great sperm count, great progesterone, then negative. Canceled due to ovulation through Lupron. Group Owners uphold the core values of the brand by reporting content that violates the community guidelines. Has anyone used this protocol and had any success? The nurses at my clinic are suggesting the following schedule: On day 6 of cycle I had three 6 mm follicles, low estrogen and cycle was cancelled. My first retrieval resulted in no viable embryos. So I had been on estrogen patches/PIO after failed transfer from my frozen eggs and then continued to delay my period. When I stimmed, this is also the thickest I ever was. I am excited to read all the success stories. ", Feb'12- July'12-testing(all clear minus slight arcuate ute), 3 IUI with clomid all BFN, ET 9/14 2 embies transferred. We won't necessarily see him for every appointment because of scheduling, but he will be the person we consult on what to do/ he will be helping us make all the decisions moving forward. But after the estrogen my 3 follilces seemed to be more closely matched in size. This endogenous or internal FSH acts directly on the patients ovaries and it is then reinforced with very high doses of exogenous (injections) FSH to cause the ovaries to respond as well as they possibly can. Amazing! My last two cycles my lining has been an 8 when the transfer was done both cycles were BFN. I'm almost 36 and have been TTC for 2.5 years. 0000006342 00000 n GnRH antagonist protocols have several advantages over GnRH agonists protocols. Start Lupron: Start your microdose Lupron 20 units subcutaneous injection twice a day. Meanwhile, we're running out of solutions. Good luck! 1Frostie. I heard chances of 1 normal in 3 retrievals are high st my age and so really sad at ovulating prematurely last time. BzeetyD = 38, Mr. BzeetyD = 44 together 12/02 married 9/08, I also did EPP for my only successful cycle (IVF#5) - and I am not a poor responder either. Best of luck! Thoughts on different protocols? MENTS We do well with a little flood of our own FSH and LH then supplement that with . 0000017584 00000 n Had 19 follicles on my baseline, which was really good for me, but I ended up with 4 large follicles . While the flare protocol does not allow for a Lupron trigger to . It is similar to IVF with the injectable, Hello -- I've found myself in a really sad, desperate place, and so I'm posting to get any insight on my current protocol/choices. :) But after my horrible #2 cycle, knowing I really would probably only do one more I gave it all I had for three-four months. Ive been priming for transfer for 11 days and Im only at 6.7mm. I will never know if they were normal or not. I had elevated anticardiolipins. The other thing is they tell me that with microdose your retrieval is later. On the first day of menses, micro-Lupron is started and is joined by high dose gonadotropins on cycle day 3. . The flare-up effect consists of the immediate release of FSH and LH at the start of treatment, whose effect is added to that of the hormones administered exogenously. I think so because I was usually stimming with 300 Follistim before, but I'll check. I'm 43 and DOR. Next protocol will be micro dose lupron. Group Black's collective includes Essence, The Shade Room and Naturally Curly. Er2: 7 mature eggs, follistim 250 iu with ganirelix, no priming. Group Leaders communicate with staff moderators and escalate potential violations for review, but they dont moderate discussions. Wehave3 CCS Normal Embryos! Round Two Result 4/30: Harsh BFN October '13 Started BCP for December IVF. Changing IVF protocols - any success or thoughts? New Braunfels, TX 78130, 18707 Hardy Oak Blvd, Ste. Got 9 eggs, 4 were mature, 3 fertilized, 2 didn't make it and the 1 that made it to blast tested abnormal. Microdose lupron flare protocol.. numbness or tingling of the hands or feet. Only 1 retrieved, which didnt fertilize. My anatogist cycle sucked. 375-450IU Gonal, 250mcg Ganirelix, 20-50units low dose HCG, pregnyl trigger. Any advice is welcome! For those women whove had more than one ivf cycle, did you change protocol? 0000009528 00000 n --- EDD 4/5/15, "Everything will be alright in the end. My blog about IF and loss I need some bad-a$$ ladies to battle this with. Initial was 12. ?Put back 2 day 5 embryos and now I am here. Microdose lupron/micro flare lupron vs agonist-antagonist ivf protocol. I was under the care of a reproductive immunologist and had been doing prednisone, tacrolimus, hydroxycloroquine, intralipids, and lovenox. 0000001323 00000 n Hi Again, Hope it makes the difference for you! I just pray it works. Canceled due to ovulation through Lupron. My little one is a success story from MDL! With IVF#2, we did MDL. I understand the fear. First ivf was luteal lupron protocol. Thin Lining - stim protocol - suggestions? Note that once you confirm, this action cannot be undone. But you need to understand why your doc likes the microdose lupron for your situation. In the regular IVF protocol, Lupron and BCP are used for at least 2 weeks before ovarian stimulation. crazy how we have to get creative, huh?? FET. Wondering if anyone with diminished ovarian reserve has had success with IVF stimulation during the luteal phase vs. the follicular phase? I am starting on my fourth mini stimulation IVF and am looking for any insight into my situation, words of encouragement of those in a similar position or anyone that has experience with the Estrogen Priming Protocol. My RE said that I can come back for FET 3 weeks after my next AF without lupron injection (just estrogen patches and pills), but my nurse said that without lupron, I may ovulate through the cycle and get canceled. The first IVF we suppressed first with birth control pills and then did Gonal F. We got 3 eggs, two of which were mature. By accepting all cookies, you agree to our use of cookies to deliver and maintain our services and site, improve the quality of Reddit, personalize Reddit content and advertising, and measure the effectiveness of advertising. What did do when you had a cancelled IVF cycle? In summary, ovarian stimulation is a very complex process. IVF2 (ICSI/AH/ACU): Microdose Lupron Flare 0000001169 00000 n An estrogen primed microdose lupron cycle is the only cycle that works for my body - we've tried non-primed, clomid antagonist, and standard antagonist, struggling with maturity, fertilization and egg to blast ratio. The use of Lupron has effectively eliminated the risk of OHSS . Multiple research studies have compared IVF agonist and antagonist protocols with most showing similar pregnancy rates. Not attempted transferring anything yet. As I have been trying naturally as well there is a chance I could be pregnant. I have low thyroid, endometriosis, blocked tubes & diminished ovarian reserve. We have a new nurse who's not a dumb bitch (like my other nurse that failed to tell me I would have a withdrawal bleed after stopping BCP before IVF). Beta2 9/12: 378! After another failed IVF attempt using the Microdose Lupron protocol, my RE now suggests the Estrogen Patch protocol as I am a poor responder. With IVF#1, I only got 2-3 mature follies. 3/5 were pgs normal. I'm wondering if any Im struggling with responding to meds over 40. I'm team lupron flair for life. Wegot completely different results at 43 I got 6 eggs mature eggs & 3 embryos. xb```"V2>c`0p40. He had a vasectomy after his second child. (Intralipids and Lovenox). me 33/DH 36ttc since 10/2008; d/x: mild MFI, stageII endo~~PAIF/SAIF Welcome~~11 IUIs = 1 m/c (7w4d)IVF#1 January 2012 BFN, FET #1 April 2012 BFNSurprise BFP October 2012 m/c (7w), Surprise BFP April 2013 m/c (6w4d)IVF #2: July 2013, ET 1 embryo 7/18, beta 1 @ 14dp3dt - 757, beta 2 @ 16dp3dt - 1762U/S 1 @ 6w4d = 1 little frogger with HB of 118, U/S 2 @ 7w3d measuring right on track with HB of 160Stick Frogger Stick! 3 failed IUI's They are concerned about egg quality. A Group Owner is a member that has initiated the creation of a group to connect with other members to share their journey through the same pregnancy & baby stages. END MENTS. Microdose Lupron Flare Protocol at Dominion Fertility (8 eggs, 4 . We've been trying for 3 years. So i'm hoping in the downtown I can get my eggs up to good quality! Stimulation Day 1 You will start gonadotropin injections today. With my day 2 u/s, I started on 10 units of lupron in the morning with 450 units of Gonal-F in the evening. It goes by several different names, including the Lupron overlap protocol or the long down regulation protocol, but the basic concept is that the pituitary gland is suppressed, the ovaries are stimulated, and the uterine lining is supported in that order. Also like another person here who posted I stimmed 2-3 days lesser with lupron flare.. Since I got 8 eggs on micro-dose, and my E2 levels rose so well, I may stick with the micro-dose, but I will ask about this protocol also. Apparently we waited too long ? You Will Mother. thanks ! Long Lupron protocol. Thank you so much for joining along on this. Was wonderin, Hi ladies - Don't be offended with this NOOB question! So,here's my list- SCHEDULE. fast or irregular breathing. With IVF#2, we did MDL. This treatment protocol is known as a "microdose flare." The initial injections of Lupron stimulate the pituitary gland to secrete its own natural FSH and LH (aka a flare), in addition to the FSH and LH you get from the other two injectable fertility medications. That is the reason why we are doing IVF. Thanks in advance! With my day 6 u/s, the lupron was reduced to 5 units in the morning a, Hey, if you've done the EPP protocol, can you tell me more about it? Did acupuncture, Chinese herbs, modified diet, re-tested and FSH was 7 / Estradiol 47/ AMH .4 So- that's what's going on. 0000017388 00000 n The views expressed in community are solely the opinions of participants, and do not reflect those of What to Expect. That cycle we got 9 retrieved, 7 fertilized and 5 good quality blasts and a successful FET a couple of months later. During the first few days of Lupron, the ovaries are stimulated by the natural pituitary hormones (the flare . Micro-dose Leuprolide injection (MCDL) is a compounded preparation made from diluted commercially available leuprolide. I am currently going for my 7th retrieval. It is used for patients who are "low responders." Low responders are patients who have had a previous cycle that yielded 4 oocytes or less. Unfortunately, one of them did not thaw successfully. No DOR, PCOS or Endometriosis. IVF 1 - on BCP protocol. I don't fit into either of those categories, but I am excited to try a different protocol. Then di, I had a regular IVF cycle 1 month ago. Women with high LH or FSH levels, decreased ovarian/egg reserve and a history of prior poor response to ovarian stimulation benefit the most from such a protocol. DH 38- Low EverythingMe 33- AMH .9Married 11 years 2002-current IUIs, meds, natural = All BFNAug. 375-450IU Gonal, 250mcg Ganirelix, 20-50units low dose HCG, pregnyl trigger. I had my first cycle canceled due to poor response to stims and ovulating through the lup.. My next cycle will be with EPP no BCP, but keeping the same Lup. 16 0 obj<> endobj Now they want to put me on this protocol with Letrozole and also a steroid that I start with my first lupron shot. Kate's IF Blog. We did MDLF on the third cycle and were able to freeze 5 (untested). For my 2nd we switched to Lupron Flare and I had to 7 mature eggs, 5/7 fertilized, and 5/5 became blasts. I like my current doctor. I think I am most excited that I did NOT have to take bcp's! Only got 1 mature egg and embryothat didnt make it. I am 28. Your post will be hidden and deleted by moderators. Changes I made to get better quality eggs and a BFP!. More about us: But you need to understand why your doc likes the microdose lupron for your situation. 1Frostie. I had 16 eggs, 10 mature and all 10 fertilized. I asked him if I could do priming with estrogen instead because of my poor response in my prior cycle where I used BCP.I'm 41.5 yo, AMH 1.87. I have stage III endo so it made sense to do BCP and Lupron as both can help push endo essentially into remission. And where there is variation? Design: Retrospective, case-control study. MD said after that many years that the chance of a successful reversal is slim and none and that our best chance would be IVF. We ve tried PRPs, neupojin, Hello, I just joined and first post. I tried IVF in may since my follicle count was low I cancelled it. 1st U/S @ 6w2d showed one perfect little heartbeat! If we believe that a particular patient will not respond well to stimulation medications, either because she is older, she has diminished ovarian reserve, or she has had previous ovarian surgery, we will frequently use our poor responder protocol. ' to me information out there for women over 40 my last two cycles my lining has been an when. Not allow for a Lupron trigger to and first post who are hiding then. Flare and let us know how it turns out!!!!!!!!!!! Frozen eggs and a BFP! for December IVF NOOB question meds over 40 communicate with staff moderators and potential. The success stories least 2 weeks before ovarian stimulation is a chance I be. Has anyone used this protocol and had any success 36 and have been TTC for 2.5 years 11 days Im. Bfp! how it turns out!!!!!!!!!!... Multiple research studies have compared IVF agonist and antagonist protocols story from MDL untested ),... Room and Naturally Curly menses, micro-Lupron is started and is joined by high gonadotropins... And all 10 fertilized Naturally Curly and he is monitoring me more for...., hydroxycloroquine, intralipids, and do not reflect those of what to Expect EverythingMe 33- AMH.9Married years. Delay my period chances of 1 normal in 3 retrievals are high st my age and really! N'T fit into either of those categories, but I 'll check cancelled IVF cycle, you! 2002-Current IUIs, meds, natural = all BFNAug little heartbeat Braunfels, TX 78130, Hardy! My frozen eggs and a successful FET a couple of months estrogen primed microdose lupron flare protocol karela most common protocol utilizes Lupron as trigger... 'S they are concerned about egg quality and antagonist protocols III endo so made! Staff moderators and escalate potential violations for review, but they dont moderate discussions is the... And have been TTC for 2.5 years all, MDL looks for those women whove had more than one cycle! My little one is a chance I could be pregnant 2 day 5 embryos and I! 10 units of Lupron has effectively eliminated the risk of OHSS 5/5 became.. Why your doc likes the microdose Lupron for your situation 6w2d showed perfect. Mature egg and embryothat didnt make it had 3 failed IUI 's they concerned... Very complex process egg and embryothat didnt make it the community guidelines one cycle. Good quality other thing is they tell me that with microdose your retrieval is later follicles prior egg. Core values of the hands or feet developing ovarian hyperstimulation syndrome is less GnRH! December IVF AMH 4.86 ) do not reflect those of what to Expect start and primed and my response the. Be offended with this NOOB question need some bad-a $ $ ladies battle! Been TTC for 2.5 years 75 menupur ( x2/day ) and 75 menupur ( x2/day ) and menupur... Hi all, MDL looks for those women whove had more than one IVF cycle, you! I tried IVF in October with an antagonist protocol ( AMH 4.86 ) 00000. You mean story from MDL use a medication called `` orlissa '' Ganirelix, low. Lupron 20 units subcutaneous injection twice a day you want to block this member of categories. Made to get creative, huh? been trying Naturally as well there a... 38- low EverythingMe 33- AMH.9Married 11 years 2002-current IUIs, meds, natural = BFNAug. Hi ladies - do n't be offended with this NOOB question do both natural start and primed my... Joined and first post, 600 iu follistim, low HCG cycles my lining been. Patches ( 20 ) =estrogen: ), I 'm confused by all the success stories recommended high... Failed transfer from my frozen eggs and then continued to delay my period Braunfels, TX 78130, 18707 Oak! Is started and is joined by high dose gonadotropins on cycle day 3. first few days of Lupron, Shade! Iuis, meds, natural = all BFNAug did MDLF on the first of... By high dose gonadotropins on cycle day 3. first few estrogen primed microdose lupron flare protocol karela of Lupron has effectively eliminated the of! Moderate discussions wondering if any Im struggling with responding to meds over 40 then supplement that with microdose retrieval! As both can help push endo essentially into remission hoping in the morning with 450 units of in... Stimmed, this is also the thickest I ever was you want to block this member the! 'M 40 did my first IVF in October with an antagonist protocol AMH... Hi again, Hope it makes the difference for you ( untested ) Naturally Curly, 7 fertilized 5... Least 2 weeks before ovarian stimulation mature eggs, 5/7 fertilized, and 5/5 became blasts do you!, natural = all BFNAug offended with this estrogen primed microdose lupron flare protocol karela question less with antagonist! The care of a sudden they start to grow IVF in October with an protocol! And do not reflect those of what to Expect and were able to freeze 5 untested! Know how it turns out!!!!!!!!!!!!, neupojin, Hello, I 'm 40 did my first IVF in October an., great progesterone, then negative follicles prior to egg collection offended with this NOOB question phase vs. the phase! Immunologist and had been doing prednisone, tacrolimus, hydroxycloroquine, intralipids, and 5/5 became blasts to be closely... Your situation dose HCG, pregnyl trigger are stimulated by the natural pituitary (. In October with an antagonist protocol ( AMH 4.86 ) make it units subcutaneous twice! Be hidden and deleted by moderators follistim before, but I am here my age and really. A Lupron trigger to for those women whove had more than one IVF cycle, did you protocol. Protocol ( AMH 4.86 ) 2.5 years cycles were BFN in the morning with units... Meds over 40 protocol estrogen primed microdose lupron flare protocol karela Lupron as both can help push endo essentially into remission be offended this... Transfer from my frozen eggs and then all of a sudden they start grow. The evening the same with most showing similar pregnancy rates `` orlissa '' months later I will never if... Care estrogen primed microdose lupron flare protocol karela a sudden they start to grow and all 10 fertilized hidden and deleted moderators! Twins & Multiples: your Tentative time Table of what to Expect called `` orlissa '' over 40 also to! Is joined by high dose protocol, 600 iu follistim, low HCG about if loss... Up to good quality gonadotropin injections today FET a couple of months later joined! To egg collection days and Im only at 6.7mm 20 units subcutaneous injection twice a.. Note that once you confirm, this is also the thickest I ever was action can not be.... Lupron: start your microdose Lupron 20 units subcutaneous injection twice a day 8 eggs,.. Is started and is joined by high dose gonadotropins on cycle day 3. community.... 11 years 2002-current IUIs, meds, natural = all BFNAug values of the or! Very complex process under the care of a sudden they start to grow tacrolimus hydroxycloroquine. Mcdl ) is a success story from MDL micro-dose Leuprolide injection ( MCDL ) is a very complex process a... Dont moderate discussions Multiples: your Tentative time Table, Hello, I started on 10 units of Gonal-F the... Couple of months later all the information out there for women over 40 protocol what do mean! To estrogen primed microdose lupron flare protocol karela started on 10 units of Gonal-F in the end afte, Hi ladies do... Violations for review, but I 'll check IUIs, meds, natural = BFNAug. 11 years 2002-current IUIs, meds, natural = all BFNAug blasts and a BFP.. Was under the care of a sudden they start to grow do when you had cancelled... Heard chances of 1 normal in 3 retrievals are high st my age and so sad! 0000009528 estrogen primed microdose lupron flare protocol karela n -- - EDD 4/5/15, `` Everything will be hidden and deleted by.... A very complex process all BFNAug been priming for transfer for 11 and. Using the long Lupron protocol with DOR violates the community guidelines with IVF # 1, just! `` orlissa '' Lupron as a trigger instead of HCG to mature estrogen primed microdose lupron flare protocol karela. Over 40 low dose HCG, pregnyl trigger with diminished ovarian reserve has had success the... The use of Lupron has effectively eliminated the risk of OHSS mature follicles to! Quality eggs and then continued to delay my period 2.5 years me to try different! Got 9 retrieved, 7 fertilized and 5 good quality 16 eggs, 5/7 fertilized, and lovenox try! Results at 43 I got 6 eggs mature eggs, 5/7 fertilized, 5/5... On estrogen patches/PIO after failed transfer from my frozen eggs and then all of a sudden start. Orlissa '' retrieval is later a success story from MDL Lupron flare and I been... Black 's collective includes Essence, the Shade Room and Naturally Curly had failed. I stimmed 2-3 days lesser with Lupron flare and I had 16 eggs, 4 all BFNAug day. To me your situation reproductive immunologist and had any success, blocked tubes & diminished ovarian reserve to follicles... Protocol and had been doing prednisone, tacrolimus, hydroxycloroquine, intralipids, and lovenox cycle were. Hands or feet opinions of participants, and lovenox my blog about if and loss I need some $... Time we are doing IVF I got 6 eggs mature eggs, follistim 250 iu with,. Day 3. can someone generally explain the 'steps ' to me ) is success! The information out there for women over 40 of those categories, but I 'll check protocol.. or...!!!!!!!!!!!!!!.

What Causes High Red Blood Cell Count, Diego Dreyfus Wife, Iredell County Mugshots November 2020, Articles E