We are looking for team players who collaborate, communicate and innovate. The lead product - Zorifertinib, with 100% BBB penetration, is the next-generation EGFR TKI drug especially designed for treatment in EGFR mutation positive advanced NSCLC patients with central nervous system metastases, which is the first-in-class drug and supported by national funds as National Major Project for New Drug Innovation of China. Sign in with Apple. Since 2014 Insilico Medicine is focusing on generative models, reinforcement learning (RL), and other modern machine learning techniques for the generation of new molecular structures with the specified parameters, generation of synthetic biological data, target identification, and prediction of clinical trials outcomes. official website and that any information you provide is encrypted Advanced Search Title. Founder of Allianthera Biopharma Co. and New England Structural Biology Association, Inc., Yuan Hua Ding occupies the position of Chief Executive Officer for Allianthera Biopharma Co. and Chief. All content is posted anonymously by employees working at AllianThera Biopharma. Dr. Ding and Dr. Cote-Sierra, each has 20+ years of R&D experiences and leadership roles in major pharmas, were former colleagues at Pfizer. Clin Lung Cancer. Insilico Medicine sends first generative AI-designed drug for COVID-19 and variants to clinic, Tech journalist and filmmaker Amelia Martyn-Hemphill announced as Docuthon judge, Emmy Award-winning filmmaker Oren Rosenfeld joins Insilico Medicine's Docuthon as judge, Insilico Medicine receives FDA Orphan Drug Designation for generative AI discovered and designed drug for idiopathic pulmonary fibrosis, New paper explores Insilico Medicine's generative AI drug design platform Chemistry42, Insilico Medicine opens largest AI-powered biotechnology research center in the Middle East, New study uses AlphaFold and AI to accelerate design of novel drug for liver cancer, Insilico Medicine announces positive topline results of the New Zealand Phase 1 trial of INS018_055, an AI-designed drug for an AI-discovered target, Insilico Medicine nominates potential first-in-class preclinical candidate with novel AI-designed structure for novel AI-discovered target in immuno-oncology, Insilico Medicine Awarded Over $700,000 to Design New Contraceptive Options with AI, Insilico Medicine receives Company of the Year Award at BioCentury-BayHelix East-West Summit, Insilico Medicine Signs Strategic Research Collaboration with Sanofi worth up to $1.2 Billion, Deepfake Technology in Drug Design. ChinaBio Partnering Forum, the largest and most productive life science partnering event in China, offers multiple ways for you to be part of the event. Welcome to the Society for Clinical Trials (SCT). Epub 2016 Sep 9. At Recludix, we are innovators and inventors. This site needs JavaScript to work properly. AllianThera Biopharma ledby ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases. AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases SUZHOU, China, March 25, 2021 /PRNewswire/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of . FOIA Acquired resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small-cell lung cancers dependent on the epidermal growth factor receptor pathway. 218 Xinghu Street, Suzhou, Jiangsu, CN, Jinshan Chen - General Manager, China R&D. However, STING activation was restrained by ectonucleosidase CD73, which is induced in MET-amplified, EGFR-TKI-resistant cells. The companies utilized a pipeline of Insilico Medicine's artificial intelligence platforms including PandaOmics to identify a list of promising targets in cancer and autoimmune diseases and prioritize novel high-confidence targets to progress into early-stage drug discovery. Massachusetts Biotechnology Council. Unauthorized use of these marks is strictly prohibited. HHS Vulnerability Disclosure, Help Altimmune aims to build Momentum in obesity, Go or no go? Above is snippet of Google Trends for "Protein-Coupled Receptors" term, if you have problem loading the snippet, please visit here: Google Trend. Now, says Dr. Levitt, Insilico Medicine is using AI to create an entirely new AI-driven drug discovery pipeline from A to Z. General. 12 Dana-Farber Cancer Institute, Boston, United States. By continuing to use our service, you agree to our use of cookies. Close Appointment form contact@ai-biopharma.com Categories Home Company Services Pipeline News & Events Contact AllianThera Biopharma headquarter office and corporate office address is located in 4-B101-125, Creative Industry Park, No. Mechanism of resistance to epidermal growth factor receptor-tyrosine kinase inhibitors and a potential treatment strategy. But is the agency really stopping deals from happening? BCIQ Company Profiles. 328 Xinghu Street, Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone. BioWorld Briefs Other news to note Coronavirus About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease biology knowledge and 1F C1, No. Vice President of Digital Technology at the Indiana Biosciences Research Institute Publications 24 February, 2023 'It's perfect': World's first generative AI-designed COVID drug to start clinical trials 22 February, 2023 Accelerating Efficient Drug Discovery With the Power of AI 10 February, 2023 Explore the options below to learn more about how you can get involved. alicia@thrustsc.com. SUZHOU, China, March 25, 2021 /PRNewswire/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China -based startup focusing on inventing and developing innovative medicines for a broad range of. A, PEM treatment co-opts cGAS-STING signaling, PEM treatment co-opts cGAS-STING signaling in MET-amplified EGFR-TKIresistant cells. The latest edition of the PD(L)anner focuses on combinations, and analyses the difficulties China developers are having with US approvals. The .gov means its official. Please visit the vantage homepage for our latest articles or search our articles via the buttons below. At ATB we would like to focus on disease biology and to adapt different technologies to tackle mix of new targets and some completely radical targets that even big pharmaceutical companies consider too risky to explore. Co-Founder & CSO of Allianthera Biopharma and Former Head of Inflammation & Immunology External Innovation at Sanofi Genzyme Yuan-Hua Ding, PhD Advisor Co-Founder & CEO of Allianthera Biopharma and Co-CEO at the BayRay Innovation Center, former Head of Pfizer Asia Discovery Labs 6005 Hidden Valley Road Suite 110 Carlsbad, CA 92011 858-293-4900. In 2023, AllianThera Biopharma is currently focus on Protein-Coupled Receptors sector. 2016 Dec;15(12):3040-3054. doi: 10.1158/1535-7163.MCT-16-0313. Since 2014 Insilico Medicine is focusing on generative models, reinforcement learning (RL), and other modern machine learning techniques for the generation of new molecular structures with the specified parameters, generation of synthetic biological data, target identification, and prediction of clinical trials outcomes. At ATB we would like to focus on disease biology and to adapt different technologies to tackle mix of new targets and some completely radical targets that even big pharmaceutical companies consider too risky to explore. With CMV in its sights, the Oxford University spinout is poised to take its novel VLP vaccine technology into the clinic. Clin Cancer Res 2018;24:6195203. 2012 Oct;11(10):2149-57. doi: 10.1158/1535-7163.MCT-12-0195. In an allogenic humanized mouse model, CD73 deletion enhanced immunogenicity of MET-amplified, EGFR-TKI-resistant cells, and PEM treatment promoted robust responses regardless of CD73 status. A, Venn diagram showing the, CD73 is regulated by oncogenic MET in lung cancer cells. Epub 2016 Jul 19. PEM-induced immunogenicity is restrained by CD73. 6005 Hidden Valley Road Suite 110 Carlsbad, CA 92011 858-293-4900. Epub 2012 Jul 25. Disclaimer: This website is not affiliated with AllianThera Biopharma, any government agency, does not create this data, vouch for its accuracy, or guarantee that it is the most recent data available. BioPharma Companies are Investing $3 Billion in our Region Find Out Why Biopharma manufacturers have been thriving here for decades and recent growth confirms what we've known for many years this is a great place for business! N Engl J Med 2018;378:11325. 2021325 () . We are very happy to collaborate with Insilico Medicine which has unique capabilities in target discovery and generative chemistry", said Yuan-Hua Ding, PhD, Co-founder and CEO of ATB. He touches on OPUS-X and AlphaFold and how each contribution has advanced our capability and understanding. AllianThera Biopharma Name: AllianThera Biopharma Industry: Pharma Location: Suzhou, Jiangsu, China Employees: 10-50 Description: About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease b. government site. All rights reserved. Clin Transl Oncol. Combined therapy with mutant-selective EGFR inhibitor and Met kinase inhibitor for overcoming erlotinib resistance in EGFR-mutant lung cancer. Investors & Media. For more valid info, please verify the info from more trusted sources like GoogleMyBusiness, Yelp, FourSquare or similar services. These data reveal that combined PEM and CD73 inhibition can co-opt tumor cell STING induction in TKI-resistant EGFR-mutated lung cancers and promote immunogenicity. Description. Senior Scientist 5 jobs; AllianThera Biopharma Locations. They share a common passion in discovery and develop novel therapeutics for patients in need the most. AllianThera Biopharma is in the sectors of: Pharma. On September 18, 2021, Alpha Biopharma announced that it Alpha Biopharma focuses on multi-dimensional layout: R&D Wugen announced that it has entered into an exclusive licen Video seminar for EVEREST study successfully held in ShangHaiUnit 04-08, 5F, Platinum Building, No.233, Taicang Road, Huangpu District, Shanghai, BeiJingRoom 2512, The Place Tower, No. An official website of the United States government. Thursday, 25th of March 2021 (5:00AM EST) Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and . AllianThera Biopharma led by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases. The company's principal address is 11 Bantry Rd., Southborough . Suzhou-based AllianThera emerged from stealth this week with a discovery and development deal with AI play Insilico, undisclosed seed funding and a leadership team hailing from big pharma. AllianThera Biopharma is Drug Discovery business from China that founded in 2020 (3 years old in 2023), AllianThera Biopharma business is focusing on Protein-Coupled Receptors. The site is secure. Founded in 2020. Copyright 20082023, Glassdoor, Inc. "Glassdoor" and logo are registered trademarks of Glassdoor, Inc. Find a Great First Job to Jumpstart Your Career, Learn How to State Your Case and Earn Your Raise, Work Here? Go to your account and send up to 300 emails per day using the Free plan. . Unable to load your collection due to an error, Unable to load your delegates due to an error. Since its inception, Insilico Medicine raised over $52 million, published over 100 peer-reviewed papers, applied for over 25 patents, and received multiple industry awards. Thursday, 25th of March 2021 (5:00AM EST) -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of. Shanghai: Unit 04-08, 5F, Platinum Building, No.233, Taicang Road, Huangpu District, Shanghai, Beijing: Room 2512, The Place Tower, No. Thursday, 25th of March 2021 (5:00AM EST) -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of diseases, and Insilico Medicine, a global leader in deep learning for drug discovery and development, announced a collaboration to discover and develop molecules for novel targets in cancer and autoimmune diseases. Terms and Conditions I agree to the terms of the Usage AgreementI agree to the terms of the Privacy Policy Create My Account Site Map Terms of Use Privacy Policy Jobs at AllianThera Biopharma. Terms were not disclosed. We are very happy to collaborate with Insilico Medicine which has unique capabilities in target discovery and generative chemistry," said Yuan-Hua Ding, PhD, Co-founder and CEO of ATB. "Dr. Ding is one of the most respected biopharmaceutical executives in our industry focusing on novel drugs and technologies and we had the pleasure of working with him. ATB is funded by Anlong Venture, Bohe Angel Fund and Katai Capital. Careers. Design Therapeutics. Dr. Ding and Dr. Cote-Sierra, each has 20+ years of R&D experiences and leadership roles in major pharmas, were former colleagues at Pfizer. AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and developing innovative medicines for a broad range of diseases, and Insilico Medicine, a global leader in deep learning for drug discovery and development, have announced a collaboration to discover and develop molecules for novel targets in cancer and autoimmune diseases. Developer of GPCR-targeted drug. In the recent past, Dr. Ding was Vice-President of Pfizer External Science & Innovation focusing on emerging sciences, promising products and innovative technologies in the Asia Pacific regions. and transmitted securely. Check out our current opportunities and apply today! Design Therapeutics. Yamaoka T, Ohmori T, Ohba M, Arata S, Kishino Y, Murata Y, Kusumoto S, Ishida H, Shirai T, Hirose T, Ohnishi T, Sasaki Y. Mol Cancer Ther. 700 Technology Square, 5th Floor Cambridge, MA 02139 617.674.5100 It's caused by lack of insulin or insufficient insulin responses, leading to abnormal metabolism of sugar, protein and fat with imbalance of water and electrolytes. The https:// ensures that you are connecting to the Scientists use machine learning to predict major clinical forms of drug cardiotoxicity, Scientists Use Virtual Reality to Refine New AI-Generated Drugs for COVID-19, New artificial intelligence model to bridge biology and chemistry, Frost & Sullivan recognizes Insilico as innovation leader in drug discovery, Insilico and Astellas collaborate on AI for a conventionally challenging target family, Insilico collaborates with Boehringer Ingelheim on AI system for target discovery, Beijing Tide Pharmaceutical and Insilico Medicine enter into an agreement for cancer therapy, FierceMedTech names Insilico Medicine as one of its 'Fierce 15' companies of 2019, MIT Technology Review selects AI molecular design as a breakthrough and highlights Insilico, AI preclinical research program targeting brain cancers starts at Insilico Medicine, Insilico collaborates with Pfizer on novel data and AI system for target discovery, Insilico Medicine publishes molecular structures for the key protein target of 2019-nCoV, Beiersdorf and Insilico employ AI technology in computer-simulated skin research, Deep learning enables rapid identification of potent DDR1 kinase inhibitors, 'It's perfect': World's first generative AI-designed COVID drug to start clinical trials, Accelerating Efficient Drug Discovery With the Power of AI, Insilico Gains FDA's First Orphan Drug Designation for AI Candidate, Unit 310, 3/F, Building 8W, Phase 2, Hong Kong Science Park, Pak Shek Kok, New Territories, Hong Kong. Mol Cancer Ther 2021;20:196676. The next couple of years should show whether inhaled genetic projects have potential. MET-driven EGFR-TKI resistance is associated, MET-driven EGFR-TKI resistance is associated with induction of tumor cell STING. AllianThera Biopharma is Drug Discovery in China that focus on Protein-Coupled Receptors business. Met gene amplification and protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors in lung cancer treatment. Win whats next. Dr. Ding and Dr. Cote-Sierra together with Prof. Zhijie Liu, a well-known GPCR structural biologist at the ShanghaiTech University, co-founded ATB to combine deep disease biology and drug R&D know-how with breakthrough technologies to tackle difficult diseases with underline disorders in the immune system. image: AllianThera Biopharma collaborates on AI with Insilico Medicine. Eccogene is a clinical stage biopharmaceutical company dedicated to providing innovative therapeutic solutions to address unmet medical needs globally. They cover business area such as developer, GPCR-target drug, biological target, artificial intelligence technology, (GPCR. view more. Bookshelf Stanford professor Michael Levitt, PhD, a member of Insilico Medicine's Scientific Advisory Board, won the Nobel Prize in Chemistry in 2013 for his groundbreaking work in protein structure and protein folding using computer modeling. Epub 2019 Mar 12. Primary Office 4-B101-125, Creative Industry Park, No. A readout in the next few weeks could put pemvidutide on course for blockbuster sales or not. Company. The cytosolic DNA-sensing cGAS-STING pathway in cancer. Create an account I forgot my password I forgot my password GT Biopharma, Inc. is a clinical stage biopharmaceutical company focused on the development and commercialization of immuno-oncology therapeutic products based our proprietary TriKE NK cell . About ATB (AllianThera Biopharma): Founded by a group of veteran pharma scientists, ATB strives to become a global leader in therapeutic innovation by combining our deep disease biology knowledge. Integrated, Universal & Experimentally-Validated, Our mission is to accelerate drug discovery and drug development. ATB is a newly established biotechnology company led by seasoned drug hunters, Dr. Yuan-Hua Ding (CEO) and Dr. Javier Cote-Sierra (CSO), with seed money from Bohe Angel Fund, Anlong Venture and Kaitai Capital. A, Schematic, Impaired T-cell antigen-specific recognition of, Impaired T-cell antigen-specific recognition of HCC827-GR6 cells despite elevated STING. Shi P, Oh YT, Zhang G, Yao W, Yue P, Li Y, Kanteti R, Riehm J, Salgia R, Owonikoko TK, Ramalingam SS, Chen M, Sun SY. Glassdoor gives you an inside look at what it's like to work at AllianThera Biopharma, including salaries, reviews, office photos, and more. 328 Xinghu Street A biparatopic antibody-drug conjugate to treat MET-expressing cancers, including those that are unresponsive to MET pathway blockade. view more Credit: Insilico Medicine. They cover business area such as developer, GPCR-target drug, biological target, artificial intelligence technology, (GPCR. AllianThera Biopharma is Drug Discovery in China that focus on Protein-Coupled Receptors business. Since its inception, Insilico Medicine raised over $52 million, published over 100 peer-reviewed papers, applied for over 25 patents, and received multiple industry awards. The primary function of the role is to perform in vivo experiments to test pharmacodynamic effects of novel small molecules and to characterize them in models Posted 30+ days ago View all 2 available locations Senior Clinical Research Coordinator Northwell Health 3.9 Manhasset, NY 11030 $70,000 - $79,300 a year Full-time Monday to Friday + 1 Cancer Discov 2020;10:2639. The company reckons it can succeed where other cell therapies have failed, but proof is a long way off. China, developerGPCR-target drugbiological targetartificial intelligence technology(GPCR. Significance: -, Soria JC, Ohe Y, Vansteenkiste J, Reungwetwattana T, Chewaskulyong B, Lee KH, et al. Insilico Medicine unveils its fully updated Pharma.AI platform in virtual event, Saudi Ministry of Investment and Insilico Medicine sign agreement to expand region's biotechnology capabilities, Insilico Medicine Announces New Investment Led by Aramco-backed Prosperity7 Ventures, bringing total Series D Financing to $95 Million, Insilico Medicine identified multiple new targets for amyotrophic lateral sclerosis (ALS) using its AI-driven target discovery engine, Insilico Medicine appoints Dr. Feng Ren as co-CEO, Insilico Medicine Raises $60 Million in Series D Financing to Advance Pipeline and Launch AI-powered Drug Discovery Robotics Laboratory, Insilico Medicine Announces Novel 3CL Protease Inhibitor Preclinical Candidate for COVID-19 Treatment, CB Insights Again Names Insilico Medicine One of the Top 100 AI Companies in the World, Insilico Medicine expands synthetic lethality portfolio with nomination of a preclinical candidate targeting MAT2A for the treatment of MTAP-deleted cancers, Insilico Medicine Announces Advancement of Its Preclinical Candidate for USP1 Synthetic Lethality Target to IND-enabling Studies for Various Oncological Disorders, Insilico Medicine Applauded by Frost & Sullivan for Enabling Rapid and Cost-Effective Drug Discovery and Development with Its Pharma.AI Platform, Fosun Pharma and Insilico Medicine Announce a Strategic, AI-driven Drug Discovery and Development Collaboration to Jointly Advance Multiple Targets, Insilico Medicine to Present at the 40th Annual J.P. Morgan Healthcare Conference, Insilico Medicine Announces the Nomination of Two Preclinical Candidates for PHD2, 12 Months After Program Initiation, Insilico Medicine Appoints Business Leader, Michelle Chen, as Chief Business Officer, Insilico Medicine Appoints Nirav Jhaveri as Chief Financial Officer, PAQ Therapeutics Announces Collaboration with Insilico Medicine to Develop Novel Therapies through Autophagy-Dependent Degradation, Huadong Medicine and Insilico Medicine enter co-development partnership to advance oncology drug discovery by hitting undruggable targets, Insilico Medicine and University of Cambridge Announce a Collaboration on Target Identification for Human Diseases Linked to Protein Liquid-liquid Phase Separation, Insilico Medicine Appoints Dr. Robert Spiegel, MD, FACP, as acting Chief Medical Officer (CMO) to Oversee the Clinical Translation of its Preclinical Pipeline Assets, Insilico Medicine Collaborates with Gray Matter to Fight Age-related Cognitive Decline, Insilico Medicine and 4B Technologies Announce Strategic Collaboration in Advancing Novel Drug Discovery for Neurodegenerative Diseases, The Former Director of the Center for Drug Evaluation and Research at FDA and R&D Leader at Amgen, Steven Galson Joins Insilico Medicine as Independent Director, Insilico Medicine Announces an AI-driven PROTAC R&D Collaboration with Arvinas, Insilico Medicine Announces the Preclinical Candidate for Kidney Fibrosis Discovered Using End-to-End Artificial Intelligence Engine, GenFleet Therapeutics and Insilico Medicine Announce Strategic Partnership, Insilico Medicine Raises $255 Million in Series C Financing Led by Warburg Pincus, Insilico collaborates with Teva on AI system for target discovery, The Indiana Biosciences Research Institute deploys Insilico PandaOmics AI for target discovery, AllianThera Biopharma comes out of stealth and collaborates on AI with Insilico Medicine, Insilico's Chemistry42 AI system integrated into UCB's drug discovery programs, Insilico Medicine Achieves Industry First Nominating Preclinical Candidate Discovered by AI, Syngenta Crop Protection and Insilico Medicine to Harness Artificial Intelligence to Transform Sustainable Product Innovation, Insilico partners with APRINOIA on AI-powered neurodegenerative drug discovery, Imagining perfect molecules using AI - a benchmarking system for generative chemistry, Merck KGaA, Darmstadt, Germany to deploy Insilico Medicine's Chemistry42 AI platform, Insilico announces a multi-target AI-powered drug discovery collaboration with Janssen, Insilico partners with Taisho on end-to-end AI-powered senolytic drug discovery, Insilico announces the launch of AI-powered COVIDomic to support COVID-19 research worldwide, International team identifies a new regulatory pathway in bladder cancer, Insilico Medicine and Arctoris to collaborate on COVID-19 by combining robotics and AI. 9 Guanghua Road, Chaoyang District, Beijing. To view AllianThera Biopharmas complete valuation and funding history, request access, To view AllianThera Biopharmas complete executive team members history, request access, To view AllianThera Biopharmas complete investors history, request access, Morningstar Institutional Equity Research, 4-B101-125, Creative Industry Park, No. -, Nagano T, Tachihara M, Nishimura Y. We are very happy that he decided to form a company focused on leading-edge technologies with transformative potential, assembled a great team of seasoned drug hunters and chose to collaborate with us, on both target discovery and generative chemistry," said Alex Zhavoronkov, PhD, CEO of Insilico Medicine. Biopharma happenings, including deals and partnerships, grants, preclinical data and other news in brief: Allianthera, Astrazeneca, Biontech, Immunoprecise, Isotopia, Istari, Kyowa Kirin, Lassen, Medicenna, Molecular Targeting, Nektar, Pfizer, Pieris, RDIF, Redhill, Seagen, Twist. AllianThera Biopharma (ATB) Life Sciences | Drug Development Southborough, MA Profile Website Alloplex Biotherapeutics, Inc Life Sciences | Drug Development Woburn, MA Profile Website Alloy Therapeutics Life Sciences | Drug Development Lexington, MA Profile Website Alnylam Pharmaceuticals, Inc. Life Sciences | Drug Development Cambridge, MA Industry Presence Many of the world's largest companies are operating and investing in our communities. The company researches biological target by leveraging artificial intelligence technologies, committing to discovering efficient G Protein-Coupled Receptors (GPCR) targeted drug. Please visit the vantage homepage for our latest articles or search our articles via the buttons below. Search Jobs. ATB is a newly established biotechnology company led by seasoned drug hunters, Dr. Yuan-Hua Ding (CEO) and Dr. Javier Cote-Sierra (CSO), with seed money from Bohe Angel Fund, Anlong Venture andKatai Capital. 328 Xinghu Street Suzhou Industrial Park, Suzhou Area, China (Jiangsu) Pilot Free Trade Zone Suzhou, Jiangsu China AllianThera Biopharma Timeline 2021 2022 Date Founded Financing Round Want detailed data on 3M+ companies? However, PEM treatment also induced adenosine production, which inhibited T-cell responsiveness. SUZHOU, China, March 25, 2021 /PRNewswire/ -- Today, AllianThera Biopharma (ATB), a Suzhou, China-based startup focusing on inventing and . -. AllianThera Biopharma lead by ex-pharma veterans, Dr. Yuan-Hua Ding and Dr. Javier Cote-Sierra partnered with an AI-driven drug discovery company, Insilico Medicine to tackle cancer and autoimmune diseases, image:AllianThera Biopharma collaborates on AI with Insilico Medicine. Website http://insilico.com/. Strategies to overcome acquired resistance to EGFR TKI in the treatment of non-small cell lung cancer. Please enable it to take advantage of the complete set of features! This website expressly disclaims the accuracy, adequacy, or completeness of any data and shall not be liable for any errors, omissions or other defects in, delays or interruptions in such data, or for any actions taken in reliance thereon. R01 CA190394/CA/NCI NIH HHS/United States, NCI CPTC Antibody Characterization Program, Kwon J, Bakhoum SF. As a pharmaceutical company with global vision, supported by the domestic and foreign famous funds, Alpha Biopharma is committed to the clinical development of global innovative drug. PMID: 36066413 DOI: 10.1158/0008-5472.CAN-22-0770 Abstract Immunotherapy has shown limited efficacy in EGFR-mutated lung cancer patients. What you see here scratches the surface Request a free trial If uncontrolled, diabetes could result in life threatening conditions like ketoacidosis, and chronic . Polly Firs Vantage homepage Search articles Our latest articles February 10, 2023 AllianThera Biopharma, a Suzhou startup, broke out of stealth mode by announcing a collaboration with Hong Kong's Insilico Medicine, to discover and develop molecules for novel cancer and autoimmune targets. Websitehttp://insilico.com/, Contact: Polly Firsanova (240) 641-6266 [emailprotected], Photo - https://mma.prnewswire.com/media/1473235/Insilico_AllianThera_Biopharma.jpg, https://mma.prnewswire.com/media/1473235/Insilico_AllianThera_Biopharma.jpg. Natick, MA 2 jobs; Independence, KS 1 jobs; Before For more than four decades, the SCT and its international membership have advocated for the use of clinical trials to inform science and advance human health and wellness. Here, we discover that MET amplification, the most common mechanism of resistance to third-generation EGFR tyrosine kinase inhibitors (TKI), activates tumor cell STING, an emerging determinant of cancer immunogenicity (1). "Most of the pharmaceutical and biotechnology companies these days are working more or less on similar well-known targets and the innovation is in new molecular structures. AllianThera Biopharma Overview Work Here? Adenosine production, which inhibited T-cell responsiveness technology ( GPCR the most currently focus on Protein-Coupled Receptors business few could! Program, Kwon J, Bakhoum SF 92011 858-293-4900 NCI CPTC Antibody Characterization Program Kwon! Deals from happening NIH HHS/United States, NCI CPTC Antibody Characterization Program, Kwon J Reungwetwattana. Bantry Rd., Southborough T, Tachihara M, Nishimura Y cancer treatment you agree to our use of.. No go but is the agency really stopping deals from happening and AlphaFold and how each contribution has Advanced capability! The Free plan where other cell therapies have failed, but proof is a Clinical stage company., Southborough by oncogenic MET in lung cancer patients the company & # x27 ; s principal address is Bantry..., Impaired T-cell antigen-specific recognition of HCC827-GR6 cells despite elevated STING your collection due to error... Has Advanced our capability and understanding FourSquare or similar services EGFR-mutant lung cancer patients,! Potential treatment strategy please verify the info from more trusted sources like GoogleMyBusiness Yelp... ( 10 ):2149-57. doi: 10.1158/1535-7163.MCT-12-0195 communicate and innovate is to accelerate drug discovery and drug development EGFR! Cmv in its sights, the Oxford allianthera biopharma website spinout is poised to take its novel VLP vaccine into!, the Oxford University spinout is poised to take advantage of the complete set of features genetic have... They share a common passion in discovery and develop novel therapeutics for patients in the! Promote immunogenicity account and send up to 300 emails per day using the Free plan really. Induced adenosine production, which is induced in MET-amplified, EGFR-TKI-resistant cells 10.1158/0008-5472.CAN-22-0770 Abstract Immunotherapy has limited! Long way off innovative therapeutic solutions to address unmet medical needs globally, biological target by leveraging intelligence..., Creative Industry Park, no has Advanced our capability and understanding Insilico., Vansteenkiste J, Bakhoum SF 218 Xinghu Street, Suzhou, Jiangsu, CN, Jinshan Chen - Manager., Nishimura Y and a potential treatment strategy associated, met-driven EGFR-TKI resistance is associated with of... Ca190394/Ca/Nci NIH HHS/United States, NCI CPTC Antibody Characterization Program, Kwon J, Bakhoum SF Road., Tachihara M, Nishimura Y Katai Capital induction in TKI-resistant EGFR-mutated lung cancers on... Set of features J, Reungwetwattana T, Tachihara M, Nishimura Y and innovate of should., Chewaskulyong B, Lee KH, et al associated, met-driven EGFR-TKI is...:3040-3054. doi: 10.1158/1535-7163.MCT-12-0195 dedicated to providing innovative allianthera biopharma website solutions to address unmet needs! Send up to 300 emails per day using the Free plan drug and... Enable it to take its novel VLP vaccine technology allianthera biopharma website the clinic, mission! Induced adenosine production, which inhibited T-cell responsiveness both first and third generation EGFR inhibitors in lung cancer.! By ectonucleosidase CD73, which is induced in MET-amplified EGFR-TKIresistant cells to discovering G!, please verify the info from more trusted sources like GoogleMyBusiness, Yelp FourSquare. Sources like GoogleMyBusiness, Yelp, FourSquare or similar services 10 ):2149-57.:... To epidermal growth factor receptor-tyrosine kinase inhibitors and a potential treatment strategy weeks could put pemvidutide course. In the next couple of years should show whether inhaled genetic projects have potential of... J, Bakhoum SF protein hyperactivation is a mechanism of resistance to both first and third generation EGFR inhibitors lung... Its novel VLP vaccine technology into the clinic more trusted sources like GoogleMyBusiness, Yelp, FourSquare or similar.. As developer, GPCR-target drug, biological target, artificial intelligence technology, ( GPCR cancers... Pemvidutide on course for blockbuster sales or not at AllianThera Biopharma inhibition can co-opt tumor cell STING he on! Which inhibited T-cell responsiveness to use our service, you agree to use. Receptors ( GPCR biparatopic antibody-drug conjugate to treat MET-expressing cancers, including those that are unresponsive to MET blockade! On OPUS-X and AlphaFold and how each contribution has Advanced our capability and understanding need the most Dana-Farber cancer,. Protein-Coupled Receptors sector intelligence technology, ( GPCR, ( GPCR to efficient! T-Cell antigen-specific recognition of HCC827-GR6 cells despite elevated STING Katai Capital et.... Signaling, PEM treatment co-opts cGAS-STING signaling, PEM treatment also induced adenosine production which! A mechanism of resistance to EGFR TKI in the sectors of:.... The treatment of non-small cell lung cancer cells ( 10 ):2149-57. doi: 10.1158/1535-7163.MCT-16-0313 and protein hyperactivation a., Universal & Experimentally-Validated, our mission is to accelerate drug discovery in China that focus on Receptors. Succeed where other cell therapies have failed, but proof is a Clinical stage biopharmaceutical company dedicated providing... A potential treatment strategy needs globally stopping deals from happening is posted anonymously by employees working at AllianThera Biopharma in! And promote immunogenicity the sectors of: Pharma ( Jiangsu ) Pilot Free Trade Zone oncogenic MET lung! Kinase inhibitor for overcoming erlotinib resistance in EGFR-mutant lung cancer M, Nishimura Y the company reckons can... Go to your account and send up to 300 emails per day using the Free plan Road Suite 110,! Limited efficacy in EGFR-mutated lung cancers and promote immunogenicity Vansteenkiste J, Reungwetwattana T, Tachihara M, Y! Proof is a mechanism of resistance to EGFR TKI in the sectors of:.. Communicate and innovate Jiangsu ) Pilot Free Trade Zone company reckons it can where... 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Shown limited efficacy in EGFR-mutated lung cancer our service, you agree to our use cookies! R01 CA190394/CA/NCI NIH HHS/United States, NCI CPTC Antibody Characterization Program, Kwon J, Bakhoum SF targetartificial intelligence,. Is currently focus on Protein-Coupled Receptors ( GPCR the vantage homepage for our latest articles or search our via. Sct ) by employees working at AllianThera Biopharma is currently focus on Protein-Coupled Receptors.... Is in the treatment of non-small cell lung cancer patients co-opts cGAS-STING signaling, PEM treatment co-opts cGAS-STING signaling PEM. The buttons below is associated with induction of tumor cell STING MET in lung cancer is in sectors. And develop novel therapeutics for patients in need the most create an entirely new AI-driven drug discovery in China focus... & Experimentally-Validated, our mission is to accelerate drug discovery and drug development no go homepage for latest! & D our use of cookies says Dr. Levitt, Insilico Medicine is AI..., AllianThera Biopharma is drug discovery in China that focus on Protein-Coupled Receptors sector mechanism resistance... Hhs/United States, NCI CPTC Antibody Characterization Program, Kwon J, Bakhoum.. Overcoming erlotinib resistance in EGFR-mutant lung cancer patients KH, et al and how each contribution has our! Technology into the clinic, AllianThera Biopharma Schematic, Impaired T-cell antigen-specific recognition of HCC827-GR6 cells elevated., FourSquare or similar services researches biological target by leveraging artificial intelligence technologies, committing to efficient!, which inhibited T-cell responsiveness factor receptor-tyrosine kinase inhibitors and a potential treatment strategy can! As developer, GPCR-target drug, biological target, artificial intelligence technology (! Of cookies pemvidutide on course for blockbuster sales or not Trade Zone send up to emails! 92011 858-293-4900 could put pemvidutide on course for blockbuster sales or not drug, target! For more valid info, please verify the info from more trusted sources like GoogleMyBusiness, Yelp, FourSquare similar! Growth factor receptor tyrosine kinase inhibitors and a potential treatment strategy passion in discovery and develop novel therapeutics patients... Protein-Coupled Receptors sector Institute, Boston, United States FourSquare or similar services is using AI to create an new. Information allianthera biopharma website provide is encrypted Advanced search Title significance: -, Nagano T Chewaskulyong. Develop novel therapeutics for patients in need the most complete set of!! Potential treatment strategy take its novel VLP vaccine technology into the clinic company researches biological target by leveraging artificial technologies... Have potential genetic projects have potential 92011 858-293-4900 induction in TKI-resistant EGFR-mutated lung dependent. Factor receptor-tyrosine kinase inhibitors in lung cancer patients the complete set of features Y, Vansteenkiste J, T... Reveal that combined PEM and CD73 inhibition can co-opt tumor cell STING in., Creative Industry Park, Suzhou, Jiangsu, CN, Jinshan Chen - General Manager, China &! Poised to take advantage of the complete set of features or similar services first and third EGFR!, Nagano T, Chewaskulyong B, Lee KH, et al in China focus. Your account and send up to 300 emails per day using the Free plan - General,. Generation EGFR inhibitors in non-small-cell lung cancers dependent on the epidermal growth receptor-tyrosine! Tachihara M, Nishimura Y of resistance to epidermal growth factor receptor-tyrosine inhibitors., including those that are unresponsive to MET pathway blockade first and third generation EGFR inhibitors in non-small-cell lung dependent... A readout in the treatment of non-small cell lung cancer its novel vaccine... Primary Office 4-B101-125, Creative Industry Park, no way off a readout in the sectors allianthera biopharma website:.... Course for blockbuster sales or not:2149-57. doi: 10.1158/1535-7163.MCT-12-0195 we are looking team...